| Date | Opponent | City | Stadium | Broadcast |
| 9/6/26 | Wisconsin (Shamrock Series) | Green Bay, WI | Lambeau Field | TBA |
| 9/12/26 | Rice | Notre Dame, IN | Notre Dame Stadium | TBA |
| 9/19/26 | Michigan State | Notre Dame, IN | Notre Dame Stadium | TBA |
| 9/26/26 | at Purdue | West Lafayette, IN | Ross-Ade Stadium | TBA |
| 10/3/26 | at North Carolina | Chapel Hill, NC | Kenan Memorial Stadium | TBA |
| 10/10/26 | Stanford | Notre Dame, IN | Notre Dame Stadium | TBA |
| 10/17/26 | at BYU | Provo, UT | LaVell Edwards Stadium | TBA |
| 10/24/26 | BYE | |||
| 10/31/26 | at Navy | Foxborough, MA | Gillette Stadium | TBA |
| 11/7/26 | Miami | Notre Dame, IN | Notre Dame Stadium | TBA |
| 11/14/26 | Boston College | Notre Dame, IN | Notre Dame Stadium | TBA |
| 11/21/26 | SMU | Notre Dame, IN | Notre Dame Stadium | TBA |
| 11/28/26 | at Syracuse | Syracuse, NY | JMA Wireless Dome | TBA |
